RGS10 anticorps (Middle Region)

N° du produit ABIN2792213

L’anticorps Lapin Polyclonal anti-RGS10 a été validé pour WB et FACS. Il convient pour détecter RGS10 dans des échantillons de Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour RGS10 anticorps (Middle Region) (ABIN2792213)

Antigène: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS10 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-RGS10 anticorps

Épitope: Middle Region

Séquence: DQIFNLMKYD SYSRFLKSDL FLKHKRTEEE EEDLPDAQTA AKRASRIYNT

Homologie: Cow: 81%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 90%, Rat: 90%

Attributs du produit: This is a rabbit polyclonal antibody against RGS10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RGS10

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 181 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RGS10

Antigène: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Autre désignation: RGS10

Sujet: RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G(I)-ALPHA and G(Z)- alpha but fails to interact with the structurally and functionally distinct G(S)-alpha subunit. Activity on G(Z)-alpha is inhibited by palmitoylation of the G-protein.
Protein Interaction Partner: UBC, ADRB2, APP, PRKACA, GNAI3, GNAO1, GNAI1, GNAZ, GNRHR, CALM1, ACP6, SAP18, EIF6,
Protein Size: 181

Poids moléculaire: 21 kDa

ID gène: 6001

NCBI Accession: NM_001005339, NP_001005339

UniProt: Q96GN0

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling