NAPA anticorps (N-Term)
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- Antigène Voir toutes NAPA Anticorps
- NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))
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Épitope
- N-Term
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Reactivité
- Souris, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NAPA est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MDNSGKEAEA MALLAEAERK VKNSQSFFSG LFGGSSKIEE ACEIYARAAN
- Homologie
- Cow: 100%, Dog: 100%, Mouse: 78%, Zebrafish: 78%
- Attributs du produit
- This is a rabbit polyclonal antibody against NAPA. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human NAPA
- Top Product
- Discover our top product NAPA Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 295 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))
- Autre désignation
- NAPA (NAPA Produits)
- Synonymes
- anticorps SNAPA, anticorps wu:fa26c04, anticorps zgc:63906, anticorps napb, anticorps 1500039N14Rik, anticorps AW209189, anticorps RA81, anticorps SNARE, anticorps a-SNAP, anticorps hyh, anticorps alpha-SNAP, anticorps Alpha-SNAP, anticorps NSF attachment protein alpha, anticorps N-ethylmaleimide-sensitive factor attachment protein, alpha b, anticorps NSF attachment protein alpha L homeolog, anticorps N-ethylmaleimide-sensitive factor attachment protein, alpha, anticorps N-ethylmaleimide sensitive fusion protein attachment protein alpha, anticorps soluble NSF attachment protein, anticorps NAPA, anticorps napab, anticorps napa.L, anticorps napa, anticorps EHI_000300, anticorps Napa, anticorps LOC102577508
- Sujet
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The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37 % , 60 %, and 67 % identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively.
Alias Symbols: SNAPA
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, RNF2, ATP4A, STX5, ITGA4, FN1, VCAM1, VCP, DHX40, DHX29, THUMPD3, STAM2, VAMP2, APP, NSF, TRPC3, RTN4, STX12, GNA12, STX8, GOSR2, GOSR1, BNIP1, STX7, VAMP8, SNAP23, STX4, STX1A, SNAP25,
Protein Size: 295 - Poids moléculaire
- 33 kDa
- ID gène
- 8775
- NCBI Accession
- NM_003827, NP_003818
- UniProt
- P54920
- Pathways
- Synaptic Vesicle Exocytosis, Asymmetric Protein Localization
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