VEGFR2/CD309 anticorps (N-Term)
Aperçu rapide pour VEGFR2/CD309 anticorps (N-Term) (ABIN2792307)
Antigène
Voir toutes VEGFR2/CD309 (VEGFR2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- KDR Antibody - N-terminal region
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Séquence
- LNVGIDFNWE YPSSKHQHKK LVNRDLKTQS GSEMKKFLST LTIDGVTRSD
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Homologie
- Cow: 86%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against KDR. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human KDR
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
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Autre désignation
- KDR
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Sujet
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Background Information: KDR is the receptor for VEGF or VEGFC. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Gene Name: Kinase insert domain receptor (a type III receptor tyrosine kinase)
Alternative Symbols: FLK1, CD309, VEGFR, VEGFR2
Protein Name: Vascular endothelial growth factor receptor 2
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Poids moléculaire
- 151kDa
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ID gène
- 3791
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NCBI Accession
- NP_002244
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UniProt
- P35968
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Pathways
- Signalisation RTK, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
Antigène
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