Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

NFX1 anticorps (Middle Region)

NFX1 Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache) WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2792551
  • Antigène Voir toutes NFX1 Anticorps
    NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
    Épitope
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 28
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache)
    Hôte
    • 26
    • 2
    Lapin
    Clonalité
    • 26
    • 2
    Polyclonal
    Conjugué
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NFX1 est non-conjugé
    Application
    • 26
    • 13
    • 13
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    TLTGVLEREM QARPPPPIPH HRHQSDKNPG SSNLQKITKE PIIDYFDVQD
     Réactivité croisée
    Boeuf (Vache), Chien, Humain, Souris, Rat (Rattus)
    Homologie
    Cow: 85%, Dog: 85%, Human: 100%, Mouse: 76%, Rabbit: 85%, Rat: 85%
    Attributs du produit
    This is a rabbit polyclonal antibody against NFX1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human NFX1
    Top Product
    Discover our top product NFX1 Anticorps primaire
  • Indications d'application
    WB Suggested Anti-NFX1 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:312500
    Positive Control: HepG2 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1120 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
    Autre désignation
    NFX1 (NFX1 Produits)
    Synonymes
    anticorps NFX1, anticorps NFX2, anticorps 1300017N15Rik, anticorps 3000003M19Rik, anticorps NFX.1, anticorps TEG-42, anticorps Tex42, anticorps nuclear transcription factor, X-box binding 1, anticorps nuclear transcription factor, x-box binding 1, anticorps NFX1, anticorps CpipJ_CPIJ011986, anticorps nfx1, anticorps Nfx1
    Sujet
    MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
    Alias Symbols: DKFZp779G2416, MGC20369, NFX2
    Protein Interaction Partner: UBC, BMI1, HECW2, SRSF4, SRSF3, RPS19, RPS3A, RPL22, RPL17, RPL13, RPL7A, RPL6, RPL3, PABPC3, YBX1, NCL, HNRNPM, HSPA1A, HNRNPU, HNRNPH1, HNRNPA2B1, HIST1H2AE, EEF1A2, DMD, DDX5, FAM208B, PABPC1, RPL13A, LARP1, APC2, MATR3, HIST1H4E, USP9X, SIN3A, MAML3,
    Protein Size: 1120
    Poids moléculaire
    124 kDa
    ID gène
    4799
    NCBI Accession
    NM_002504, NP_002495
    UniProt
    Q12986
Vous êtes ici:
Support technique