MAX anticorps (N-Term)

N° du produit ABIN2792669

Cet anticorps Lapin Polyclonal détecte spécifiquement MAX dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour MAX anticorps (N-Term) (ABIN2792669)

Antigène: MAX (MYC Associated Factor X (MAX))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAX est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAX anticorps

Épitope: N-Term

Séquence: MSDNDDIEVE SDADKRAHHN ALERKRRDHI KDSFHSLRDS VPSLQGEKAS

Réactivité croisée: Chien, Poulet, Humain, Souris, Rat (Rattus)

Homologie: Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against MAX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the n terminal region of human MAX

Information d'application

Indications d'application: WB Suggested Anti-MAX Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: COLO205 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 151 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAX

Antigène: MAX (MYC Associated Factor X (MAX))

Autre désignation: MAX

Sujet: MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown. The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.
Alias Symbols: MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, orf1, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8
Protein Interaction Partner: USP37, UNC45A, BANP, FBXW11, MXI1, RPL35, TUBA1A, RPL34, GABBR1, FUS, FTH1, MYC, MXD1, MGA, PLIN3, HSP90AA1, TCF3, MYCN, CPSF6, ARL6IP5, KMT2D, HNRNPH2, DYNC1H1, CSTF2, SNIP1, PPP1CC, PPP1CB, PPP1CA, USF1, PCGF6, EP400, DMAP1, WDR5, BRD8, KAT5, MNT, MAX,
Protein Size: 151

Poids moléculaire: 17 kDa

ID gène: 4149

NCBI Accession: NM_145112, NP_660087

UniProt: P61244

Pathways: Mitotic G1-G1/S Phases