Cyclin H anticorps (Middle Region)
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- Antigène Voir toutes Cyclin H (CCNH) Anticorps
- Cyclin H (CCNH)
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Cobaye, Lapin, Cheval, Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Cyclin H est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KQKLERCHSA ELALNVITKK RKGYEDDDYV SKKSKHEEEE WTDDDLVESL
- Réactivité croisée
- Boeuf (Vache), Humain, Souris, Porc, Rat (Rattus)
- Homologie
- Cow: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 78%, Rat: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against CCNH. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CCNH
- Top Product
- Discover our top product CCNH Anticorps primaire
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- Indications d'application
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WB Suggested Anti-CCNH Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: MCF7 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Commentaires
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Antigen size: 323 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Cyclin H (CCNH)
- Autre désignation
- Cyclin H (CCNH Produits)
- Synonymes
- anticorps zgc:114132, anticorps cak, anticorps p34, anticorps p37, anticorps Cych, anticorps ACYPI004637, anticorps ccnh, anticorps Cyclin-H, anticorps 142767_at, anticorps CG7405, anticorps Dmel\\CG7405, anticorps CAK, anticorps 6330408H09Rik, anticorps AI661354, anticorps AV102684, anticorps AW538719, anticorps ccnh-A, anticorps cyclin H, anticorps cyclin-H, anticorps Cyclin H, anticorps CYclin H, anticorps cyclin H L homeolog, anticorps CCNH, anticorps ccnh, anticorps LOC5577539, anticorps Cych, anticorps CycH, anticorps cyh-1, anticorps Ccnh, anticorps ccnh.L
- Sujet
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CCNH belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAK, p34, p37
Protein Interaction Partner: SFN, GOLGA2, SSX2IP, CCDC170, CCDC33, DUSP12, SSSCA1, NDC80, CALCOCO2, PPFIA1, PSMA1, KLC3, RPA3, RPA2, RPA1, NEDD4, CDK7, CDK8, CDK2, CCNC, MNAT1, MBP, CTD, CDK20, CTBP2, CSNK2B, TRIM8, GANAB, RARB, POLR2A, GTF2H4, ERCC2, tat, POLR2B, CDK9, BRCA1, GTF2H1
Protein Size: 323 - Poids moléculaire
- 38 kDa
- ID gène
- 902
- NCBI Accession
- NM_001239, NP_001230
- UniProt
- P51946
- Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase
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