GIP anticorps (N-Term)

N° du produit ABIN2793043

Cet anticorps Lapin Polyclonal détecte spécifiquement GIP dans WB, IHC et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour GIP anticorps (N-Term) (ABIN2793043)

Antigène: GIP (Gastric Inhibitory Polypeptide (GIP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GIP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-GIP anticorps

Épitope: AA 7-38, N-Term

Fonction: Rabbit Anti-Human GIPR (N-term) Antibody

Immunogène: This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-38 amino acids from the N-terminal region of human GIPR.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of GIPR antibody (N-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.000 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur GIP

Antigène: GIP (Gastric Inhibitory Polypeptide (GIP))

Autre désignation: GIP

Sujet:

Target Description: GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.

Gene Symbol: GIPR

Poids moléculaire: 53157 Da

ID gène: 2696

UniProt: P48546

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism