IRF9 anticorps (N-Term)

N° du produit ABIN2797511

L’anticorps Lapin Polyclonal anti-IRF9 a été validé pour WB, IHC et IF. Il convient pour détecter IRF9 dans des échantillons de Souris.

Aperçu rapide pour IRF9 anticorps (N-Term) (ABIN2797511)

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-IRF9 anticorps

Épitope: AA 75-104, N-Term

Fonction: Rabbit Anti-Mouse IRF9 (N-term) Antibody

Immunogène: This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the N-terminal region of human IRF9.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50IRF9 Antibody (N-term) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.280 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur IRF9

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Autre désignation: IRF9

Sujet:

Target Description: IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Gene Symbol: IRF9

Poids moléculaire: 43696 Da

ID gène: 10379

UniProt: Q00978

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Hepatitis C