PUMA anticorps (BH3 Domain)

N° du produit ABIN2798057

L’anticorps Lapin Polyclonal anti-PUMA a été validé pour WB, IHC, IF et FACS. Il convient pour détecter PUMA dans des échantillons de Humain.

Aperçu rapide pour PUMA anticorps (BH3 Domain) (ABIN2798057)

Antigène: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PUMA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-PUMA anticorps

Épitope: AA 119-154, BH3 Domain

Fonction: Rabbit Anti-Human Puma BH3 Domain Antibody

Immunogène: This Puma BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50, FC: 1:10-50Western blot analysis of anti-Puma BH3 domain Pab .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.000 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur PUMA

Antigène: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Autre désignation: Puma

Sujet:

Target Description: PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.

Gene Symbol: BBC3

Poids moléculaire: 20532 Da

ID gène: 27113

UniProt: Q9BXH1

Pathways: Signalisation p53, Positive Regulation of Endopeptidase Activity