Cyclin D2 anticorps (N-Term)

N° du produit ABIN2798589

Cet anticorps anti-Cyclin D2 est un anticorps Lapin Polyclonal détectant Cyclin D2 dans WB. Adapté pour Humain.

Aperçu rapide pour Cyclin D2 anticorps (N-Term) (ABIN2798589)

Antigène: Cyclin D2 (CCND2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin D2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cyclin D2 anticorps

Épitope: AA 1-30, N-Term

Fonction: Rabbit Anti-Human CCND2 (N-term) Antibody

Immunogène: This CCND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCND2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000CCND2 Antibody (N-term) with the CCND2 gene.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur Cyclin D2

Antigène: Cyclin D2 (CCND2)

Autre désignation: CCND2

Sujet:

Target Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.

Gene Symbol: CCND2

Poids moléculaire: 33067 Da

ID gène: 894

UniProt: P30279

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases