S100B anticorps (Center)

N° du produit ABIN2798824

Cet anticorps Lapin Polyclonal détecte spécifiquement S100B dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour S100B anticorps (Center) (ABIN2798824)

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S100B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-S100B anticorps

Épitope: AA 28-56, Center

Fonction: Rabbit Anti-Human S100B/S-100 (Center) Antibody

Immunogène: This S100B/S-100 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the Central region of human S100B/S-100.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000S100B/S-100 Antibody (Center) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.500 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur S100B

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Autre désignation: S100B/S-100

Sujet:

Target Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Gene Symbol: S100B

Poids moléculaire: 10713 Da

ID gène: 6285

UniProt: P04271

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins