RAD51C anticorps (Center)
Aperçu rapide pour RAD51C anticorps (Center) (ABIN2798838)
Antigène
Voir toutes RAD51C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 169-198, Center
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Fonction
- Rabbit Anti-Human RAD51C (Center) Antibody
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Immunogène
- This RAD51C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human RAD51C.
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Isotype
- Ig Fraction
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Indications d'application
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Western Blot
Recommended Dilutions
WB: 1:1000RAD51C Antibody (Center) . -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))
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Autre désignation
- RAD51C
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Sujet
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Target Description: This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.
Gene Symbol: RAD51C
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Poids moléculaire
- 42190 Da
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ID gène
- 5889
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UniProt
- O43502
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Pathways
- Réparation de l'ADN
Antigène
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