ATF3 anticorps (C-Term)

N° du produit ABIN2799112

Cet anticorps Lapin Polyclonal détecte spécifiquement ATF3 dans WB et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour ATF3 anticorps (C-Term) (ABIN2799112)

Antigène: ATF3 (Activating Transcription Factor 3 (ATF3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-ATF3 anticorps

Épitope: AA 140-168, C-Term

Fonction: Rabbit Anti-Human ATF3 (C-term) Antibody

Immunogène: This ATF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human ATF3.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50ATF3 Antibody (C-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.300 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur ATF3

Antigène: ATF3 (Activating Transcription Factor 3 (ATF3))

Autre désignation: ATF3

Sujet:

Target Description: Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.

Gene Symbol: ATF3

Poids moléculaire: 20576 Da

ID gène: 467

UniProt: P18847

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response