ACLY anticorps (pSer455) (AbBy Fluor® 594)

N° du produit ABIN2810065

L’anticorps Lapin Polyclonal anti-ACLY a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter ACLY dans des échantillons de Humain.

Aperçu rapide pour ACLY anticorps (pSer455) (AbBy Fluor® 594) (ABIN2810065)

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACLY est conjugé à/à la AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-ACLY anticorps (AbBy Fluor® 594)

Épitope: pSer455

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human ATP citrate lyase around the phosphorylation site of Ser455

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ACLY

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Autre désignation: ATP citrate lyase

Sujet:

Synonyms: ATP citrate lyase phospho S455, ACL, ATP citrate pro-S lyase, ATP citrate synthase, Citrate cleavage enzyme, EC 2.3.3.8, A730098H14RIK, ACLY, ATP CITRATE LYASE, ATPCL, AW538652, Cce, CITRATE LYASE, CLATP, MGC124629.

Background: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

ID gène: 47

Pathways: L'effet Warburg