BCL3 anticorps (Center)

N° du produit ABIN653286

Cité dans 1 publication. Cet anticorps anti-BCL3 Polyclonal Lapin (Clone RB23954) (ABIN653286) détecte spécifiquement BCL3 dans WB, IF, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour BCL3 anticorps (Center) (ABIN653286)

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB23954

Détail du produit anti-BCL3 anticorps

Épitope: AA 249-277, Center

Specificité: This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248~277 amino acids from the Center region of human BCL3.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 AA from the Central region of human BCL3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.48 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-BCL3 (ABIN653286)

Gehrke, Wörns, Huber, Hess, Straub, Hövelmeyer, Waisman, Kim, Schuppan, Galle, Schattenberg: "Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation through insulin-sensitive metabolic transcription factors." dans: Journal of hepatology, Vol. 65, Issue 6, pp. 1188-1197, (2018) (PubMed).

Détails sur BCL3

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Autre désignation: BCL3

Sujet: BCL3 is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers.
Synonyms: Proto-oncogene BCL3, B-cell lymphoma 3 protein, BCL-3, D19S37, BCL4, BCL3

Poids moléculaire: 46800 Da

ID gène: 602

UniProt: P20749

Pathways: Signalisation NF-kappaB, Maintenance of Protein Location, Protein targeting to Nucleus