ALDH2 anticorps

N° du produit ABIN1881053

L’anticorps Lapin Polyclonal anti-ALDH2 a été validé pour WB, FACS et IHC (p). Il convient pour détecter ALDH2 dans des échantillons de Humain. Il y a 3+ publications disponibles.

Aperçu rapide pour ALDH2 anticorps (ABIN1881053)

Antigène: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALDH2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB23145

Détail du produit anti-ALDH2 anticorps

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Immunogène: This ALDH2 antibody is generated from rabbits immunized with human ALDH2 recombinant protein.

Information d'application

Indications d'application: WB: 1:1000,IHC (p): 1:50-100,FACS: 1:10-50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.33 mg/mL

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Références pour anticorps anti-ALDH2 (ABIN1881053)

Guo, Wang, Liu, Chen, Qi, Guo: "Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males." dans: World journal of gastroenterology : WJG, Vol. 14, Issue 9, pp. 1444-9, (2008) (PubMed).

Chen, Smith, Harbord, Lewis: "Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach." dans: PLoS medicine, Vol. 5, Issue 3, pp. e52, (2008) (PubMed).

Teeguarden, Bogdanffy, Covington, Tan, Jarabek: "A PBPK model for evaluating the impact of aldehyde dehydrogenase polymorphisms on comparative rat and human nasal tissue acetaldehyde dosimetry." dans: Inhalation toxicology, Vol. 20, Issue 4, pp. 375-90, (2008) (PubMed).

Détails sur ALDH2

Antigène: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Autre désignation: ALDH2

Sujet: ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.

Synonyms: ALDH2, ALDM, Aldehyde dehydrogenase, mitochondrial, ALDH class 2, ALDH-E2, ALDHI

NCBI Accession: NP_000681, NP_001191818

UniProt: P05091