Poliovirus Receptor anticorps (FITC)
Aperçu rapide pour Poliovirus Receptor anticorps (FITC) (ABIN2853601)
Antigène
Voir toutes Poliovirus Receptor (PVR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody reacts with human CD155.
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Purification
- Protein G agarose
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Immunogène
- Recombinant human CD155
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS, 0.09 % NaN3, 1 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8 °C.
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- Poliovirus Receptor (PVR)
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Autre désignation
- CD155 / PVR
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Sujet
- CD155, transmembrane glycoprotein, is a member of the immunoglobulin superfamily also known as the human receptor for poliovirus (PVR). CD155 localizes in cell-matrix adhesions and cell-cell junctions. PV receptor CD155 forms a complex with PV (PV1, PV2, and PV3). Both glycosylated and fully deglycosylated CD155 exhibited similar binding sites and orientations in the viral canyon for all three PV serotypes, showing that all three serotypes use a common mechanism for cell entry. It is reported that CD155 and CD112/nectin-2/PRR-2 are ligands of CD226/DNAM-1.Synonyms: Necl-5, Necl5, Nectin-like protein 5, PVS, Poliovirus receptor
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ID gène
- 5817
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NCBI Accession
- NP_001129240
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UniProt
- P15151
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
Antigène
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