Poliovirus Receptor anticorps (AA 28-331)

N° du produit ABIN7601071

L’anticorps anti-Poliovirus Receptor Monoclonal Souris est utilisé pour la détection de Poliovirus Receptor dans des échantillons de Humain et Souris. Il a été validé pour WB, FACS et IHC.

Aperçu rapide pour Poliovirus Receptor anticorps (AA 28-331) (ABIN7601071)

Antigène: Poliovirus Receptor (PVR)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Poliovirus Receptor est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone: 5I13D1

Détail du produit anti-Poliovirus Receptor anticorps

Épitope: AA 28-331

Fonction: Anti-Poliovirus Receptor/PVR Antibody (monoclonal, 5I13D1)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Poliovirus Receptor/PVR Antibody.(monoclonal, 5I13D1)-2. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Poliovirus Receptor/PVR recombinant protein (Position: D28-E331).

Isotype: IgG2a

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Poliovirus Receptor

Antigène: Poliovirus Receptor (PVR)

Autre désignation: PVR

Sujet:

Background: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: PVR cell adhesion molecule

Poids moléculaire: 70-80 kDa

ID gène: 5817

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome