ENPP1 anticorps

N° du produit ABIN2854438

Cet anticorps Lapin Polyclonal détecte spécifiquement ENPP1 dans WB. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour ENPP1 anticorps (ABIN2854438)

Antigène: ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ENPP1 est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: KO Validated

Détail du produit anti-ENPP1 anticorps

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1)
ENPP1 antibody [N2C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human ENPP1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HepG2 , human liver

Validation: KO/KD, Overexpression

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.14 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-ENPP1 (ABIN2854438)

Huang, Chang, Kuo, Chen, Jeng, Chang, Shew, Hu, Lee: "Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate." dans: Nature communications, Vol. 8, pp. 14706, (2018) (PubMed).

Détails sur ENPP1

Antigène: ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

Autre désignation: ectonucleotide pyrophosphatase/phosphodiesterase 1

Sujet: This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.

Poids moléculaire: 105 kDa

ID gène: 5167

UniProt: P22413

Pathways: Regulation of Carbohydrate Metabolic Process