PTK7 anticorps (C-Term)

N° du produit ABIN2854472

L’anticorps Lapin Polyclonal anti-PTK7 a été validé pour FACS. Il convient pour détecter PTK7 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour PTK7 anticorps (C-Term) (ABIN2854472)

Antigène: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTK7 est non-conjugé

Application: Flow Cytometry (FACS)

Détail du produit anti-PTK7 anticorps

Épitope: C-Term

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to CCK4 (CCK4 protein tyrosine kinase 7)
CCK4 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human CCK4. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.36 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-PTK7 (ABIN2854472)

Chen, Khatri, Mazur, Polin, Zheng, Vaka, Hoang, Shrager, Xu, Vicent, Butte, Sweet-Cordero: "A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma." dans: Cancer research, Vol. 74, Issue 10, pp. 2892-902, (2014) (PubMed).

Détails sur PTK7

Antigène: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Autre désignation: protein tyrosine kinase 7 (inactive)

Sujet: Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.

Cellular Localization: Membrane, Single-pass type I membrane protein

Poids moléculaire: 118 kDa

ID gène: 5754

UniProt: Q13308

Pathways: Signalisation RTK, Tube Formation