ATF6 anticorps (C-Term)

N° du produit ABIN2854487

L’anticorps Lapin Polyclonal anti-ATF6 a été validé pour WB. Il convient pour détecter ATF6 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour ATF6 anticorps (C-Term) (ABIN2854487)

Antigène: ATF6 (Activating Transcription Factor 6 (ATF6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF6 est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: KO Validated

Détail du produit anti-ATF6 anticorps

Épitope: C-Term

Specificité: This antibody was raised against the C-terminus of human ATF6 alpha, meaning it can only detect the uncleaved form.,Knockdown/Knockout validation was supported by references (PMID:29535165)

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit polyclonal antibody to ATF6 (activating transcription factor 6)
ATF6 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATF6. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Validatio: KO/KD, Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-ATF6 (ABIN2854487)

Wang, Lai, Yang, Lin, Chen, Tsai: "Counteracting Cisplatin-Induced Testicular Damages by Natural Polyphenol Constituent Honokiol." dans: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).

Détails sur ATF6

Antigène: ATF6 (Activating Transcription Factor 6 (ATF6))

Autre désignation: activating transcription factor 6

Sujet: ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules.[supplied by OMIM]

Cellular Localization: Endoplasmic reticulum membrane , Processed cyclic AMP-dependent transcription factor ATF-6 alpha: Nucleus

Poids moléculaire: 75 kDa

ID gène: 22926

UniProt: P18850

Pathways: ER-Nucleus Signaling, Unfolded Protein Response