CD3D anticorps (Center)
Aperçu rapide pour CD3D anticorps (Center) (ABIN2854530)
Antigène
Voir toutes CD3D AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Attributs du produit
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Rabbit Polyclonal antibody to CD3 delta (CD3d molecule, delta (CD3-TCR complex))
CD3 delta antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human CD3 delta. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:5000-1:20000*
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Commentaires
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Positive Control: Jurkat membrane
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
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Autre désignation
- CD3 delta
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Sujet
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The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Cellular Localization: Membrane -
Poids moléculaire
- 19 kDa
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ID gène
- 915
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Pathways
- TCR Signaling, CXCR4-mediated Signaling Events
Antigène
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