desert Hedgehog anticorps (Center)

N° du produit ABIN2854606

Cet anticorps Lapin Polyclonal détecte spécifiquement desert Hedgehog dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour desert Hedgehog anticorps (Center) (ABIN2854606)

Antigène: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp desert Hedgehog est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-desert Hedgehog anticorps

Épitope: Center

Réactivité croisée: Souris, Rat (Rattus)

Réactivité croisée (Details): Mouse (98 %), Rat (98 %)

Attributs du produit: Rabbit polyclonal antibody to Dhh (desert hedgehog homolog (Drosophila))
Dhh antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Dhh. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:5000-1:20000*

Commentaires:

Positive Control: 293T , A431 , Jurkat , Raji

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.95 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur desert Hedgehog

Antigène: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Autre désignation: Dhh

Classe de substances: Species

Sujet: This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

Cellular Localization: Desert hedgehog protein N-product: Cell membrane, Lipid-anchor, Extracellular side , Desert hedgehog protein C-product: Secreted , extracellular space , Desert hedgehog protein N-product: Cell membrane , Desert hedgehog protein C-product: Secreted , extra

Poids moléculaire: 44 kDa

ID gène: 50846

Pathways: Signalisation Hedgehog