VCP anticorps (C-Term)
Aperçu rapide pour VCP anticorps (C-Term) (ABIN2854929)
Antigène
Voir toutes VCP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- C-Term
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Specificité
- Knockdown/Knockout validation was supported by customer review data.
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Réactivité croisée
- Humain, Souris, Rat, Poisson zèbre (Danio rerio)
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Attributs du produit
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Rabbit Polyclonal antibody to VCP (valosin containing protein)
VCP antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the C-terminus region of human VCP. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: Mouse brain , Rat brain
Validation: KO/KD, Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "PTPN12/PTP-PEST Regulates Phosphorylation-Dependent Ubiquitination and Stability of Focal Adhesion Substrates in Invasive Glioblastoma Cells." dans: Cancer research, Vol. 78, Issue 14, pp. 3809-3822, (2019) (PubMed).
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: "PTPN12/PTP-PEST Regulates Phosphorylation-Dependent Ubiquitination and Stability of Focal Adhesion Substrates in Invasive Glioblastoma Cells." dans: Cancer research, Vol. 78, Issue 14, pp. 3809-3822, (2019) (PubMed).
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- VCP (Valosin Containing Protein (VCP))
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Autre désignation
- valosin containing protein
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Sujet
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The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
Cellular Localization: Cytoplasm , cytosol , Nucleus -
Poids moléculaire
- 89 kDa
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ID gène
- 7415
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UniProt
- P55072
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Pathways
- ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway
Antigène
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