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VCP anticorps (C-Term)

Cet anticorps anti-VCP est un anticorps Lapin Polyclonal détectant VCP dans WB, IF, IP, IHC (p), ICC, IHC (fro) et IHC (wm). Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.
N° du produit ABIN2854929

Aperçu rapide pour VCP anticorps (C-Term) (ABIN2854929)

Antigène

Voir toutes VCP Anticorps
VCP (Valosin Containing Protein (VCP))

Reactivité

  • 92
  • 50
  • 42
  • 14
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 77
  • 20
  • 2
Lapin

Clonalité

  • 68
  • 31
Polyclonal

Conjugué

  • 63
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
Cet anticorp VCP est non-conjugé

Application

  • 66
  • 36
  • 31
  • 21
  • 17
  • 15
  • 14
  • 13
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Whole Mount) (IHC (wm))

Classe de qualité

KO Validated
  • Épitope

    • 10
    • 10
    • 9
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificité

    Knockdown/Knockout validation was supported by customer review data.

     Réactivité croisée

    Humain, Souris, Rat, Poisson zèbre (Danio rerio)

    Attributs du produit

    Rabbit Polyclonal antibody to VCP (valosin containing protein)
    VCP antibody

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein encompassing a sequence within the C-terminus region of human VCP. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Commentaires

    Positive Control: Mouse brain , Rat brain

    Validation: KO/KD, Orthogonal

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chen, Morales, Guerrero, Sun, McCarty: "PTPN12/PTP-PEST Regulates Phosphorylation-Dependent Ubiquitination and Stability of Focal Adhesion Substrates in Invasive Glioblastoma Cells." dans: Cancer research, Vol. 78, Issue 14, pp. 3809-3822, (2019) (PubMed).

  • Antigène

    VCP (Valosin Containing Protein (VCP))

    Autre désignation

    valosin containing protein

    Sujet

    The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.

    Cellular Localization: Cytoplasm , cytosol , Nucleus

    Poids moléculaire

    89 kDa

    ID gène

    7415

    UniProt

    P55072

    Pathways

    ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway
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