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GBA anticorps (C-Term)

Cet anticorps anti-GBA est un anticorps Lapin Polyclonal détectant GBA dans WB, ICC, IF et IHC (p). Adapté pour Humain.
N° du produit ABIN2854995

Aperçu rapide pour GBA anticorps (C-Term) (ABIN2854995)

Antigène

Voir toutes GBA Anticorps
GBA (Glucosidase, Beta, Acid (GBA))

Reactivité

  • 71
  • 42
  • 30
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 78
  • 15
Lapin

Clonalité

  • 72
  • 21
Polyclonal

Conjugué

  • 36
  • 17
  • 11
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp GBA est non-conjugé

Application

  • 62
  • 30
  • 23
  • 14
  • 11
  • 10
  • 9
  • 9
  • 5
  • 4
  • 2
  • 1
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

     Réactivité croisée

    Chimpanzé

    Réactivité croisée (Details)

    Chimpanzee (100 %)

    Attributs du produit

    Rabbit Polyclonal antibody to GBA (glucosidase, beta, acid)
    GBA antibody [C1C3]

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein encompassing a sequence within the C-terminus region of human GBA. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

    Commentaires

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.82 mg/mL

    Buffer

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    Agent conservateur

    Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène

    GBA (Glucosidase, Beta, Acid (GBA))

    Autre désignation

    GBA

    Sujet

    This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein.

    Cellular Localization: Lysosome membrane, Peripheral membrane protein, Lumenal side

    Poids moléculaire

    60 kDa

    ID gène

    2629

    Pathways

    Cellular Glucan Metabolic Process
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