BTK anticorps (C-Term)

N° du produit ABIN2855016

Détail du produit anti-BTK anticorps

Antigène: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BTK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Boeuf (Vache), Poulet, Porc, Rat (Rattus)

Réactivité croisée (Details): Chicken (86 %), Pig (99 %), Rat (98 %), Bovine (98 %)

Attributs du produit: Rabbit Polyclonal antibody to BTK (Bruton agammaglobulinemia tyrosine kinase)
BTK antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human BTK. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: Molt-4

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.62 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur BTK

Antigène: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Autre désignation: BTK (BTK Produits)

Synonymes: anticorps BTK, anticorps atk, anticorps bpk, anticorps xla, anticorps imd1, anticorps agmx1, anticorps psctk1, anticorps AGMX1, anticorps AT, anticorps ATK, anticorps BPK, anticorps IMD1, anticorps PSCTK1, anticorps XLA, anticorps AI528679, anticorps xid, anticorps Bruton tyrosine kinase, anticorps Bruton agammaglobulinemia tyrosine kinase, anticorps BTK, anticorps btk, anticorps Btk

Sujet: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.

Cellular Localization: Cytoplasm , Membrane, Peripheral membrane protein , Nucleus , Cytoplasm , Membrane , Nucleus

Poids moléculaire: 76 kDa

ID gène: 695

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling