ARHGEF18 anticorps (Center)

N° du produit ABIN2855329

Cet anticorps Lapin Polyclonal détecte spécifiquement ARHGEF18 dans WB, IF et ICC. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour ARHGEF18 anticorps (Center) (ABIN2855329)

Antigène: ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF18 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-ARHGEF18 anticorps

Épitope: Center

Attributs du produit: Rabbit Polyclonal antibody to ARHGEF18 (Rho/Rac guanine nucleotide exchange factor (GEF) 18)
ARHGEF18 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human ARHGEF18. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.43 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-ARHGEF18 (ABIN2855329)

Haas, Zihni, Ruppel, Hartmann, Ebnet, Tada, Balda, Matter: "Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly." dans: Cell reports, Vol. 32, Issue 3, pp. 107924, (2020) (PubMed).

Lu, Wawro, Morgens, Portela, Bassik, Pfeffer: "Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs." dans: eLife, Vol. 7, (2018) (PubMed).

Zihni, Vlassaks, Terry, Carlton, Leung, Olson, Pichaud, Balda, Matter: "An apical MRCK-driven morphogenetic pathway controls epithelial polarity." dans: Nature cell biology, Vol. 19, Issue 9, pp. 1049-1060, (2017) (PubMed).

Détails sur ARHGEF18

Antigène: ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))

Autre désignation: ARHGEF18

Sujet: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.

Cellular Localization: Cytoplasm

Poids moléculaire: 131 kDa

ID gène: 23370

Pathways: Neurotrophin Signaling Pathway