ARHGEF18 anticorps (AA 159-551)

N° du produit ABIN7167973

Détail du produit anti-ARHGEF18 anticorps

Antigène: ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))

Épitope: AA 159-551

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF18 est non-conjugé

Application: ELISA, Western Blotting (WB)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Rho guanine nucleotide exchange factor 18 protein (159-551AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ARHGEF18

Antigène: ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))

Autre désignation: ARHGEF18 (ARHGEF18 Produits)

Synonymes: anticorps arhgef18, anticorps wu:fc21e04, anticorps wu:fj05f11, anticorps zgc:85686, anticorps P114-RhoGEF, anticorps AI467246, anticorps D030053O22Rik, anticorps rho/rac guanine nucleotide exchange factor (GEF) 18a, anticorps Rho/Rac guanine nucleotide exchange factor (GEF) 18, anticorps Rho/Rac guanine nucleotide exchange factor 18, anticorps rho guanine nucleotide exchange factor 18, anticorps rho/rac guanine nucleotide exchange factor (GEF) 18, anticorps arhgef18a, anticorps ARHGEF18, anticorps LOC100027283, anticorps Arhgef18

Sujet:

Background: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). p114RgoGEF cts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. It may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS), but does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.

Aliases: 114 kDa Rho specific guanine nucleotide exchange factor antibody, 114 kDa Rho-specific guanine nucleotide exchange factor antibody, ARHGEF 18 antibody, Arhgef18 antibody, ARHGI_HUMAN antibody, KIAA0521 antibody, MGC15913 antibody, p114 Rho GEF antibody, p114-Rho-GEF antibody, p114RhoGEF antibody, Rho guanine nucleotide exchange factor 18 antibody, Rho specific guanine nucleotide exchange factor p114 antibody, Rho/Rac guanine nucleotide exchange factor (GEF) 18 antibody, Rho/Rac guanine nucleotide exchange factor 18 antibody, SA RhoGEF antibody, SA-RhoGEF antibody, Septin associated RhoGEF antibody, Septin-associated RhoGEF antibody

UniProt: Q6ZSZ5

Pathways: Neurotrophin Signaling Pathway