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RRM2 anticorps (Regulatory Subunit)

L’anticorps Lapin Polyclonal anti-RRM2 a été validé pour WB, IF, IHC (p) et ICC. Il convient pour détecter RRM2 dans des échantillons de Humain. Il y a 1 publication disponible.
N° du produit ABIN2855573

Aperçu rapide pour RRM2 anticorps (Regulatory Subunit) (ABIN2855573)

Antigène

Voir toutes RRM2 Anticorps
RRM2 (Ribonucleotide Reductase M2 (RRM2))

Reactivité

  • 62
  • 14
  • 13
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 52
  • 10
Lapin

Clonalité

  • 42
  • 19
  • 1
Polyclonal

Conjugué

  • 27
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp RRM2 est non-conjugé

Application

  • 44
  • 17
  • 15
  • 13
  • 13
  • 8
  • 7
  • 7
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Classe de qualité

KO Validated
  • Épitope

    • 15
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Regulatory Subunit

     Réactivité croisée

    Humain, Souris, Rat, Poisson zèbre (Danio rerio)

    Attributs du produit

    Rabbit Polyclonal antibody to RRM2 (ribonucleotide reductase M2)
    RRM2 antibody [N1C1]

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein encompassing a sequence within the center region of human RRM2. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Commentaires

    Validatio: KO/KD, Orthogonal

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.18 mg/mL

    Buffer

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Su, Wu, Ko, Tsai, Tee, Chien, Chou, Lin, Low, Chou, Yang, Wang: "The expression of ribonucleotide reductase M2 in the carcinogenesis of uterine cervix and its relationship with clinicopathological characteristics and prognosis of cancer patients." dans: PLoS ONE, Vol. 9, Issue 3, pp. e91644, (2015) (PubMed).

  • Antigène

    RRM2 (Ribonucleotide Reductase M2 (RRM2))

    Autre désignation

    ribonucleotide reductase M2

    Sujet

    This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion.

    Cellular Localization: Cytoplasm

    Poids moléculaire

    45 kDa

    ID gène

    6241

    UniProt

    P31350

    Pathways

    Mitotic G1-G1/S Phases
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