FZD8 anticorps (C-Term)
Aperçu rapide pour FZD8 anticorps (C-Term) (ABIN2855896)
Antigène
Voir toutes FZD8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée
- Souris, Rat (Rattus), Xenopus tropicalis
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Réactivité croisée (Details)
- Mouse (100 %), Rat (100 %), Xenopus Tropicalis (100 %)
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Attributs du produit
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Rabbit Polyclonal antibody to Frizzled 8 (frizzled homolog 8 (Drosophila))
Frizzled 8 antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Frizzled 8. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:5000-1:20000*
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Commentaires
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Positive Control: H1299
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- FZD8 (Frizzled Family Receptor 8 (FZD8))
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Autre désignation
- Frizzled 8
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Sujet
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This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
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Poids moléculaire
- 73 kDa
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ID gène
- 8325
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Pathways
- Signalisation WNT
Antigène
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