ETFA anticorps (Center)
Aperçu rapide pour ETFA anticorps (Center) (ABIN2856049)
Antigène
Voir toutes ETFA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Attributs du produit
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Rabbit Polyclonal antibody to ETFA (electron-transfer-flavoprotein, alpha polypeptide)
ETFA antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human ETFA. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*
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Commentaires
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Positive Control: A431 , HeLa , PC-12
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.88 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))
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Autre désignation
- ETFA
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Sujet
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ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Mitochondrion matrix -
Poids moléculaire
- 35 kDa
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ID gène
- 2108
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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