AKAP12 anticorps (C-Term)

N° du produit ABIN2856350

Détail du produit anti-AKAP12 anticorps

Antigène: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP12 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Attributs du produit: Rabbit polyclonal antibody to AKAP12 (A kinase (PRKA) anchor protein (gravin) 12)
AKAP12 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human AKAP12. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.73 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur AKAP12

Antigène: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Autre désignation: AKAP12 (AKAP12 Produits)

Synonymes: anticorps akap12, anticorps cb27, anticorps esr1, anticorps fb72g12, anticorps id:ibd1202, anticorps sb:cb27, anticorps si:ch73-192g21.1, anticorps wu:fb72g12, anticorps wu:fc21c03, anticorps AKAP12, anticorps AI317366, anticorps SSeCKS, anticorps Srcs5, anticorps Tsga12, anticorps AKAP12A, anticorps AKAP12B, anticorps AKAP12G, anticorps AKAP250, anticorps A kinase (PRKA) anchor protein 12b, anticorps A-kinase anchoring protein 12, anticorps A kinase (PRKA) anchor protein (gravin) 12, anticorps akap12b, anticorps AKAP12, anticorps Akap12

Sujet: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Cellular Localization: Cytoplasm , cell cortex , cytoskeleton

Poids moléculaire: 191 kDa

ID gène: 9590

Pathways: cAMP Metabolic Process