AKAP12 anticorps

N° du produit ABIN306674

L’anticorps anti-AKAP12 Polyclonal Mouton est utilisé pour la détection de AKAP12 dans des échantillons de Rat. Il a été validé pour IHC, WB et IP.

Aperçu rapide pour AKAP12 anticorps (ABIN306674)

Antigène: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Reactivité: Rat

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP12 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-AKAP12 anticorps

Fonction: Sheep anti Rat SSeCKS - myristylated (PKC) substrate

Attributs du produit: Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet little is known about downstream substrates or their roles in normal or diseased states. SSeCKS, a novel protein kinase C substrate originally isolated as a src-suppressed negative mitogenic regulator in fibroblasts, controls actinbased cytoskeletal architecture and scaffolds key signaling kinases such as protein kinase C and protein kinase A. Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation. A role for SSeCKS, a PKA/PKC scaffolding protein, has been implicated during the process of spermiogenesis and in the actin-based stellate morphology of mesangial cells

Purification: Ammonium Sulfate Precipitation

Isotype: IgG

Information d'application

Indications d'application: Antibody can be used for Western blot (2-5 μg/mL), immunohistochemistry and immunoprecipitation. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/ml

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur AKAP12

Antigène: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Autre désignation: SSeCKS - myristylated (PKC) substrate

Sujet: SSeCKS, A-kinase anchor protein 12, AKAP12, src-suppressed C kinase substrate

UniProt: Q62766

Pathways: cAMP Metabolic Process