VPS35 anticorps (C-Term)

N° du produit ABIN2856562

Détail du produit anti-VPS35 anticorps

Antigène: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS35 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Poisson zèbre (Danio rerio), Poulet, Boeuf (Vache)

Réactivité croisée (Details): Zebrafish (86 %), Chicken (93 %), Bovine (100 %)

Attributs du produit: Rabbit Polyclonal antibody to VPS35 (vacuolar protein sorting 35 homolog (S. cerevisiae))
VPS35 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human VPS35. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: A549 , H1299 , HCT116 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , mouse brain , rat brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-VPS35 (ABIN2856562)

Lenoir, Ustunel, Rajesh, Kaur, Moreau, Gruenberg, Overduin: "Phosphorylation of conserved phosphoinositide binding pocket regulates sorting nexin membrane targeting." dans: Nature communications, Vol. 9, Issue 1, pp. 993, (2018) (PubMed).

Détails sur VPS35

Antigène: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Autre désignation: VPS35 (VPS35 Produits)

Synonymes: anticorps MEM3, anticorps PARK17, anticorps vps35, anticorps MGC81959, anticorps bZ34G2.3, anticorps si:rp71-34g2.3, anticorps wu:fa66e03, anticorps wu:fb95c08, anticorps zgc:136268, anticorps 23.m05999, anticorps Mem3, anticorps VPS35, anticorps DKFZp459E1510, anticorps CG5625, anticorps DVps35, anticorps Dmel\\CG5625, anticorps Dvps35, anticorps dvps35, anticorps AI647796, anticorps mem3, anticorps VPS35, retromer complex component, anticorps VPS35 retromer complex component L homeolog, anticorps VPS35 retromer complex component, anticorps vacuolar protein sorting 35 homolog (S. cerevisiae), anticorps vacuolar protein sorting-associated protein 35, anticorps vacuolar protein sorting 35, anticorps Vacuolar protein sorting 35, anticorps hypothetical protein, anticorps VPS35 retromer complex component S homeolog, anticorps retromer complex subunit Vps35, anticorps VPS35, anticorps vps35.L, anticorps vps35, anticorps Tc00.1047053511367.170, anticorps Tb10.70.5460, anticorps BBOV_IV009740, anticorps CC1G_12185, anticorps PTRG_08682, anticorps CMU_017400, anticorps PHATR_43830, anticorps MCYG_00751, anticorps MGYG_01212, anticorps EHI_086580, anticorps EHI_002990, anticorps EHI_041950, anticorps EHI_096520, anticorps Bm1_44045, anticorps LOC100285267, anticorps Vps35, anticorps PGTG_10018, anticorps Tsp_09825, anticorps vps35.S

Sujet: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.

Cellular Localization: Cytoplasm , Membrane, Peripheral membrane protein

Poids moléculaire: 92 kDa

ID gène: 55737