VPS35 anticorps (HRP)

N° du produit ABIN6932999

Détail du produit anti-VPS35 anticorps (HRP)

Antigène: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VPS35 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Ubiquitous. Highly expressed in brain, colon, heart, kidney, ovary, placenta, skeletal muscle, small intestine, testis, thymus.,Detects ~92 kDa.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Full length recombinant human VSP35

Clone: 10A8

Isotype: IgG2a

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:200)
• IP (1:200)
• optimal dilutions for assays should be determined by the user.
• optimal dilutions for assays should be determined by the user.

Commentaires:

A 1:1000 dilution of ABIN6932999 was sufficient for detection of VPS35 in 10 μg of SH-SY5Y by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur VPS35

Antigène: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Autre désignation: VPS35 (VPS35 Produits)

Synonymes: anticorps MEM3, anticorps PARK17, anticorps vps35, anticorps MGC81959, anticorps bZ34G2.3, anticorps si:rp71-34g2.3, anticorps wu:fa66e03, anticorps wu:fb95c08, anticorps zgc:136268, anticorps 23.m05999, anticorps Mem3, anticorps VPS35, anticorps DKFZp459E1510, anticorps CG5625, anticorps DVps35, anticorps Dmel\\CG5625, anticorps Dvps35, anticorps dvps35, anticorps AI647796, anticorps mem3, anticorps VPS35, retromer complex component, anticorps VPS35 retromer complex component L homeolog, anticorps VPS35 retromer complex component, anticorps vacuolar protein sorting 35 homolog (S. cerevisiae), anticorps vacuolar protein sorting-associated protein 35, anticorps vacuolar protein sorting 35, anticorps Vacuolar protein sorting 35, anticorps hypothetical protein, anticorps VPS35 retromer complex component S homeolog, anticorps retromer complex subunit Vps35, anticorps VPS35, anticorps vps35.L, anticorps vps35, anticorps Tc00.1047053511367.170, anticorps Tb10.70.5460, anticorps BBOV_IV009740, anticorps CC1G_12185, anticorps PTRG_08682, anticorps CMU_017400, anticorps PHATR_43830, anticorps MCYG_00751, anticorps MGYG_01212, anticorps EHI_086580, anticorps EHI_002990, anticorps EHI_041950, anticorps EHI_096520, anticorps Bm1_44045, anticorps LOC100285267, anticorps Vps35, anticorps PGTG_10018, anticorps Tsp_09825, anticorps vps35.S

Sujet: Vacuolar Protein Sorter-35 (VPS35) is a component of the retromer complex, which is essential for endosome-to-Golgi retrieval of membrane proteins. VPS35 mutations such as D620N have been linked to Parkinson's Disease (PD) (1,2) and affect retromer function, protein homeostasis, and mitochondria (3).

ID gène: 55737

NCBI Accession: NP_060676

UniProt: Q96QK1