RAD9A anticorps (Center)

N° du produit ABIN2857053

Détail du produit anti-RAD9A anticorps

Antigène: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD9A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Attributs du produit: Rabbit Polyclonal antibody to Rad9 (RAD9 homolog A (S. pombe))
Rad9 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Rad9. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: A431 , HeLa , C2C12 , Rat2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur RAD9A

Antigène: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Autre désignation: Rad9 (RAD9A Produits)

Synonymes: anticorps RAD9, anticorps Rad9, anticorps rad9a, anticorps MGC89062, anticorps XRad9, anticorps rad9, anticorps RAD9 checkpoint clamp component A, anticorps RAD9 checkpoint clamp component B, anticorps RAD9 checkpoint clamp component A L homeolog, anticorps RAD9A, anticorps Rad9a, anticorps rad9a, anticorps rad9b, anticorps rad9a.L

Sujet: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.

Cellular Localization: Nucleus

Poids moléculaire: 43 kDa

ID gène: 5883

Pathways: Positive Regulation of Response to DNA Damage Stimulus