RAD9A anticorps (AA 162-391)

N° du produit ABIN3022652

L’anticorps anti-RAD9A Polyclonal Lapin est utilisé pour la détection de RAD9A dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour RAD9A anticorps (AA 162-391) (ABIN3022652)

Antigène: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD9A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RAD9A anticorps

Épitope: AA 162-391

Séquence: ALAEVTLGIG RGRRVILRSY HEEEADSTAK AMVTEMCLGE EDFQQLQAQE GVAITFCLKE FRGLLSFAES ANLNLSIHFD APGRPAIFTI KDSLLDGHFV LATLSDTDSH SQDLGSPERH QPVPQLQAHS TPHPDDFAND DIDSYMIAME TTIGNEGSRV LPSISLSPGP QPPKSPGPHS EEEDEAEPST VPGTPPPKKF RSLFFGSILA PVRSPQGPSP VLAEDSEGEG

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 162-391 of human RAD9A (NP_004575.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RAD9A

Antigène: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Autre désignation: RAD9A

Sujet: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RAD9A,RAD9,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Apoptosis,RAD9A

Poids moléculaire: 42 kDa

ID gène: 5883

UniProt: Q99638

Pathways: Positive Regulation of Response to DNA Damage Stimulus