RAD9A anticorps
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- Antigène Voir toutes RAD9A Anticorps
- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp RAD9A est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Immunogène
- Recombinant Protein
- Top Product
- Discover our top product RAD9A Anticorps primaire
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anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 162-391) antibody
RAD9A Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (Center) antibodyRAD9A Reactivité: Humain, Souris, Rat WB, IHC (p), IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (pSer328) antibodyRAD9A Reactivité: Humain WB, IHC (p), DB Hôte: Lapin Polyclonal RB7115 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) antibodyRAD9A Reactivité: Humain, Singe, Chien WB, IHC, IHC (p) Hôte: Souris Monoclonal 5D9 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 365-391) antibodyRAD9A Reactivité: Humain WB, IHC (p), IF Hôte: Lapin Polyclonal RB29524 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (pSer272) antibodyRAD9A Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB7109 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 1-30) antibodyRAD9A Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB0965-RB0966 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (pSer387) antibodyRAD9A Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 264-370) antibodyRAD9A Reactivité: Humain, Souris, Rat WB, IF Hôte: Souris Monoclonal 56-hRad9 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 267-341) antibodyRAD9A Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- IP: 1:500. WB: 1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Stock
- 4 °C,-20 °C
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- Antigène
- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
- Autre désignation
- RAD9A (RAD9A Produits)
- Synonymes
- anticorps RAD9, anticorps Rad9, anticorps rad9a, anticorps MGC89062, anticorps XRad9, anticorps rad9, anticorps RAD9 checkpoint clamp component A, anticorps RAD9 checkpoint clamp component B, anticorps RAD9 checkpoint clamp component A L homeolog, anticorps RAD9A, anticorps Rad9a, anticorps rad9a, anticorps rad9b, anticorps rad9a.L
- Sujet
- Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity. Its phosphorylation by PRKCD may be required for the formation of the 9-1-1 complex.
- UniProt
- Q99638
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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