SNCAIP anticorps

N° du produit ABIN285957

Détail du produit anti-SNCAIP anticorps

Antigène: SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SNCAIP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogène: Synphilin 1 antibody was raised in goat using a peptide, SLELNGEKDKDKGRTLQRT, as the immunogen.

Information d'application

Indications d'application: ELISA: >1:10,655, IHC-P: >1:400, WB: >1:2,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur SNCAIP

Antigène: SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))

Autre désignation: Synphilin 1 (SNCAIP Produits)

Synonymes: anticorps sncaip, anticorps MGC88953, anticorps SNCAIP, anticorps LOC100221074, anticorps SYPH1, anticorps Sph1, anticorps Syph1, anticorps 2810407O15Rik, anticorps 4933427B05Rik, anticorps BB104594, anticorps synuclein alpha interacting protein, anticorps synuclein, alpha interacting protein, anticorps synuclein, alpha interacting protein (synphilin), anticorps SNCAIP, anticorps sncaip, anticorps Sncaip

Sujet: Synphilin-1 is a cytoplasmic protein that is enriched in the neurophil of normal human brain. Although the exact function of synphilin-1 is unknown, it may possibly have a role as a cytoskeletal protein based on the presence of ankyrin-like repeats and an ATP, GTP-binding domain. It has been shown to be novel is its ability to associate in vivo with a-synuclein to form cytoplasmic eosinophilic inclusions. Additionally, it has been observed to be present in Lewy bodies of Parkinson disease, which are composed of a-synuclein. Because synphilin-1 is not found in protein aggregates of Alzheimer’s disease, it appears to be specific for a-synuclein-containing lesions. Synphilin-1 may facilitate the aggregation of a-synuclein into Lewy bodies.