Tumor Protein p73 anticorps (AA 75-125)

N° du produit ABIN290398

Cet anticorps Lapin Polyclonal détecte spécifiquement Tumor Protein p73 dans WB, IHC et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Singe et Hamster.

Aperçu rapide pour Tumor Protein p73 anticorps (AA 75-125) (ABIN290398)

Antigène: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Singe, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tumor Protein p73 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Tumor Protein p73 anticorps

Épitope: AA 75-125

Specificité: This peptide sequence is 100 % conserved across multiple p73 isoforms and between rat, mouse, dog and bovine p73. Researchers are encourage to use the the immunogen sequence information and available Bioinformatics data bases to obtain additional information regarding the amino acid sizes associated with various p73 isoforms.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine (100%) Opossum, Chicken, Xenopus (90%) Bat, Rabbit, Turkey, Stickleback, Medaka, Pufferfish, Zebrafish, Nectri, Fusarium (80%).

Purification: Immunoaffinity purified

Immunogène: A synthetic peptide C-THSPYAQPSS corresponding to amino acids 95-104 of human p73, GenBank EAW71468.1. This peptide sequence is 100% conserved across multiple p73 isoforms and between rat, mouse, dog and bovine p73. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine (100%), Opossum, Chicken, Xenopus (90%), Bat, Rabbit, Turkey, Stickleback, Medaka, Pufferfish, Zebrafish, Nectri, Fusarium (80%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (5 μg/mL), WB (1 - 3 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Détails sur Tumor Protein p73

Antigène: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Autre désignation: TP73 / p73

Sujet: Name/Gene ID: TP73

Synonyms: TP73, p53-like transcription factor, p73, p53-related protein, Tumor protein p73

ID gène: 7161

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus