TBK1 anticorps (AA 440-729)
Aperçu rapide pour TBK1 anticorps (AA 440-729) (ABIN3016268)
Antigène
Voir toutes TBK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 440-729
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Séquence
- RKGIRWLIEL IKDDYNETVH KKTEVVITLD FCIRNIEKTV KVYEKLMKIN LEAAELGEIS DIHTKLLRLS SSQGTIETSL QDIDSRLSPG GSLADAWAHQ EGTHPKDRNV EKLQVLLNCM TEIYYQFKKD KAERRLAYNE EQIHKFDKQK LYYHATKAMT HFTDECVKKY EAFLNKSEEW IRKMLHLRKQ LLSLTNQCFD IEEEVSKYQE YTNELQETLP QKMFTASSGI KHTMTPIYPS SNTLVEMTLG MKKLKEEMEG VVKELAENNH ILERFGSLTM DGGLRNVDCL
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 440-729 of human TBK1/NAK (NP_037386.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TBK1 (TANK-Binding Kinase 1 (TBK1))
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Autre désignation
- TBK1
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Sujet
- The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.,TBK1,FTDALS4,NAK,T2K,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Kinase of Akt,TBK1
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Poids moléculaire
- 83 kDa
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ID gène
- 29110
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UniProt
- Q9UHD2
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
Antigène
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