Cytochrome C anticorps (AA 1-105)

N° du produit ABIN3020719

L’anticorps Lapin Polyclonal anti-Cytochrome C a été validé pour WB, IHC et IF. Il convient pour détecter Cytochrome C dans des échantillons de Humain. Il y a 4+ publications disponibles.

Aperçu rapide pour Cytochrome C anticorps (AA 1-105) (ABIN3020719)

Antigène: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cytochrome C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Cytochrome C anticorps

Épitope: AA 1-105

Séquence: MGDVEKGKKI FIMKCSQCHT VEKGGKHKTG PNLHGLFGRK TGQAPGYSYT AANKNKGIIW GEDTLMEYLE NPKKYIPGTK MIFVGIKKKE ERADLIAYLK KATNE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human Cytochrome C (NP_061820.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Cytochrome C (ABIN3020719)

Stein, Jadiya, Zhang, McLendon, Abouassaly, Witmer, Anderson, Elrod, Boudreau: "Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency." dans: Cell reports, Vol. 23, Issue 13, pp. 3710-3720.e8, (2018) (PubMed).

Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." dans: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).

Sun, Li, Yang, Shan, Zhang, Huang: "G3-C12 Peptide Reverses Galectin-3 from Foe to Friend for Active Targeting Cancer Treatment." dans: Molecular pharmaceutics, Vol. 12, Issue 11, pp. 4124-36, (2016) (PubMed).

Zhou, Xi, Wang, Fu, Jinqiang, Qiu, Jin, Xu, Huang: "Triptolide-induced oxidative stress involved with Nrf2 contribute to cardiomyocyte apoptosis through mitochondrial dependent pathways." dans: Toxicology letters, Vol. 230, Issue 3, pp. 454-66, (2014) (PubMed).

Détails sur Cytochrome C

Antigène: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Autre désignation: CYCS

Sujet: This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.,CYCS,CYC,HCS,THC4,cytochrome c,Cancer,Invasion and Metastasis,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Mitochondrial markers,Oxidative phosphorylation,Lipid Metabolism,Cytochromes,Lipases,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Lipids,CYCS

Poids moléculaire: 11 kDa

ID gène: 54205

UniProt: P99999

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity