NME1 anticorps (C-Term)

N° du produit ABIN3020815

Cet anticorps anti-NME1 est un anticorps Lapin Polyclonal détectant NME1 dans WB, IHC et IF. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour NME1 anticorps (C-Term) (ABIN3020815)

Antigène: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NME1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-NME1 anticorps

Épitope: C-Term

Séquence: MLGETNPADS KPGTIRGDFC IQVGRNIIHG SDSVESAEKE IGLWFHPEEL VDYTSCAQNW IYE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 90 to the C-terminus of human NME1/NM23A (NP_000260.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-NME1 (ABIN3020815)

Wang, Bai, Cheng, Ihsan, Zhu, Wang, Tao, Chen, Dai, Liu, Yuan: "Genomic and proteomic analysis of the inhibition of synthesis and secretion of aldosterone hormone induced by quinocetone in NCI-H295R cells." dans: Toxicology, Vol. 350-352, pp. 1-14, (2017) (PubMed).

Détails sur NME1

Antigène: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Autre désignation: NME1

Sujet: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.,NME1,AWD,GAAD,NB,NBS,NDKA,NDPK-A,NDPKA,NM23,NM23-H1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases Markers,Other Neurological disorders,Cerebralvascular accident-CVA,NME1

Poids moléculaire: 17 kDa/19 kDa/30 kDa

ID gène: 4830

UniProt: P15531

Pathways: Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process