SGK1 anticorps (AA 172-431)

N° du produit ABIN3021291

Détail du produit anti-SGK1 anticorps

Antigène: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Épitope: AA 172-431

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: LYFVLDYING GELFYHLQRE RCFLEPRARF YAAEIASALG YLHSLNIVYR DLKPENILLD SQGHIVLTDF GLCKENIEHN STTSTFCGTP EYLAPEVLHK QPYDRTVDWW CLGAVLYEML YGLPPFYSRN TAEMYDNILN KPLQLKPNIT NSARHLLEGL LQKDRTKRLG AKDDFMEIKS HVFFSLINWD DLINKKITPP FNPNVSGPND LRHFDPEFTE EPVPNSIGKS PDSVLVTASV KEAAEAFLGF SYAPPTDSFL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 172-431 of human SGK1 (NP_005618.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-SGK1 (ABIN3021291)

Li, Zhou, Yang, Li, Zhang, Wang, Jiao: "SGK1 inhibits PM2.5-induced apoptosis and oxidative stress in human lung alveolar epithelial A549 cells." dans: Biochemical and biophysical research communications, Vol. 496, Issue 4, pp. 1291-1295, (2018) (PubMed).

"Retracted: 'Anti-fibrotic actions of Ghrelin by inhibition of the NADPH oxidase-ROS signaling pathway' by Qian Wang, Xin Sui, Rui Chen, Peiyong Ma, Tao Ding, Dianjun Sui, and Ping Yang." dans: Clinical and experimental pharmacology & physiology, Vol. 45, Issue 8, pp. 885, (2018) (PubMed).

Détails sur SGK1

Antigène: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Autre désignation: SGK1 (SGK1 Produits)

Synonymes: anticorps SGK, anticorps Sgk, anticorps sgk-B, anticorps sgk2, anticorps cb1083, anticorps sgk, anticorps wu:fc20a09, anticorps sgk-A, anticorps sgk1, anticorps sgk1-a, anticorps sgk1-b, anticorps serum/glucocorticoid regulated kinase 1, anticorps Serine/threonine-protein kinase sgk-1, anticorps serum/glucocorticoid regulated kinase 1 S homeolog, anticorps serum/glucocorticoid regulated kinase 1 L homeolog, anticorps SGK1, anticorps Sgk1, anticorps sgk-1, anticorps sgk1.S, anticorps sgk1, anticorps sgk1.L

Sujet: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.,SGK1,SGK,Signal Transduction,Kinase,Serine/threonine kinases,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Stem Cells,Embryonic Stem Cells,SGK1

Poids moléculaire: 47 kDa/48 kDa/50 kDa/52 kDa/59 kDa

ID gène: 6446

UniProt: O00141

Pathways: Signalisation MAPK, Signalisation Notch, Steroid Hormone Mediated Signaling Pathway