Glutathione Peroxidase 1 anticorps (AA 50-203)

N° du produit ABIN3021456

Cet anticorps anti-Glutathione Peroxidase 1 est un anticorps Lapin Polyclonal détectant Glutathione Peroxidase 1 dans WB, IHC et IF. Adapté pour Humain.

Aperçu rapide pour Glutathione Peroxidase 1 anticorps (AA 50-203) (ABIN3021456)

Antigène: Glutathione Peroxidase 1 (GPX1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutathione Peroxidase 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Glutathione Peroxidase 1 anticorps

Épitope: AA 50-203

Séquence: GTTVRDYTQM NELQRRLGPR GLVVLGFPCN QFGHQENAKN EEILNSLKYV RPGGGFEPNF MLFEKCEVNG AGAHPLFAFL REALPAPSDD ATALMTDPKL ITWSPVCRND VAWNFEKFLV GPDGVPLRRY SRRFQTIDIE PDIEALLSQG PSCA

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 50-203 of human GPX1 (NP_000572.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Glutathione Peroxidase 1

Antigène: Glutathione Peroxidase 1 (GPX1)

Autre désignation: GPX1

Sujet: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,GPXD,GSHPX1,GPX1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Neurodegenerative Diseases,GPX1

Poids moléculaire: 10 kDa/22 kDa

ID gène: 2876

UniProt: P07203

Pathways: Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome