SOD2 anticorps (AA 25-222)

N° du produit ABIN3021904

Cet anticorps anti-SOD2 est un anticorps Lapin Polyclonal détectant SOD2 dans WB, IHC et IF. Adapté pour Humain. Ce Primary Antibody a été cité dans 8+ publications.

Aperçu rapide pour SOD2 anticorps (AA 25-222) (ABIN3021904)

Antigène: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOD2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SOD2 anticorps

Épitope: AA 25-222

Séquence: KHSLPDLPYD YGALEPHINA QIMQLHHSKH HAAYVNNLNV TEEKYQEALA KGDVTAQIAL QPALKFNGGG HINHSIFWTN LSPNGGGEPK GELLEAIKRD FGSFDKFKEK LTAASVGVQG SGWGWLGFNK ERGHLQIAAC PNQDPLQGTT GLIPLLGIDV WEHAYYLQYK NVRPDYLKAI WNVINWENVT ERYMACKK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-SOD2 (ABIN3021904)

Zhang, Geng, Liu, Li, Gao, Liu, Fang, Chang: "Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1." dans: Molecular metabolism, Vol. 6, Issue 1, pp. 138-147, (2018) (PubMed).

Hu, Nie, Chen, Xie, Fan, Wang, Long, Yan, Zhong, Yan: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." dans: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).

Zhong, Wang, Liu, Li, Huang, Zhou, Lin, Lin, Yang: "Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress." dans: Scientific reports, Vol. 5, pp. 16910, (2016) (PubMed).

Chen, An, Chen, Ye, Shen, Han, Zhang, Gao: "Chronic Exercise Training Improved Aortic Endothelial and Mitochondrial Function via an AMPKα2-Dependent Manner." dans: Frontiers in physiology, Vol. 7, pp. 631, (2016) (PubMed).

Geng, Zhang, Gao, Tao, Zhang, Liu, Fang, Chang: "Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice." dans: Biochemical and biophysical research communications, Vol. 471, Issue 4, pp. 444-9, (2016) (PubMed).

Zhang, Ouyang, Wang, Shi, Ouyang, Chen, Xiao, Fang: "Mycobacterium tuberculosis Rv2185c contributes to nuclear factor-κB activation." dans: Molecular immunology, Vol. 66, Issue 2, pp. 147-53, (2015) (PubMed).

Zhu, Dong, Sun, Ma, Yang, Zhu, Xu: "Rejuvenation of MPTP-induced human neural precursor cell senescence by activating autophagy." dans: Biochemical and biophysical research communications, Vol. 464, Issue 2, pp. 526-33, (2015) (PubMed).

Liu, Cui, Li, Xu, Zuo, Fang, Chang: "Cobalt protoporphyrin induces HO-1 expression mediated partially by FOXO1 and reduces mitochondria-derived reactive oxygen species production." dans: PLoS ONE, Vol. 8, Issue 11, pp. e80521, (2014) (PubMed).

Détails sur SOD2

Antigène: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Autre désignation: SOD2

Sujet: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.,IPO-B,IPOB,MNSOD,MVCD6,Mn-SOD,SOD2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Hypoxia,SOD2

Poids moléculaire: 18 kDa/19 kDa/20 kDa/24 kDa

ID gène: 6648

UniProt: P04179

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling