CD44 anticorps (AA 35-300)

N° du produit ABIN3021913

L’anticorps Lapin Polyclonal anti-CD44 a été validé pour WB et IHC. Il convient pour détecter CD44 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour CD44 anticorps (AA 35-300) (ABIN3021913)

Antigène: CD44

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CD44 anticorps

Épitope: AA 35-300

Séquence: HVEKNGRYSI SRTEAADLCK AFNSTLPTMA QMEKALSIGF ETCRYGFIEG HVVIPRIHPN SICAANNTGV YILTSNTSQY DTYCFNASAP PEEDCTSVTD LPNAFDGPIT ITIVNRDGTR YVQKGEYRTN PEDIYPSNPT DDDVSSGSSS ERSSTSGGYI FYTFSTVHPI PDEDSPWITD STDRIPATST SSNTISAGWE PNEENEDERD RHLSFSGSGI DDDEDFISST ISTTPRAFDH TKQNQDWTQW NPSHSNPEVL LQTTTR

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 35-300 of human CD44 (NP_001001389.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-CD44 (ABIN3021913)

Ji, Yang, Tang, Yang, Tian, Yao, Zhu, Zhang, Ji, Zheng: "Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation." dans: Nature communications, Vol. 8, pp. 15308, (2018) (PubMed).

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1,CD44,CD44,Cancer,Tumor immunology,Tumor biomarkers,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,Mesenchymal Stem Cells,CD44

Poids moléculaire: 3 kDa/15 kDa/32-53 kDa/73-81 kDa

ID gène: 960

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling