CD11b anticorps (AA 145-340)

N° du produit ABIN3022180

Cité dans 1 publication. Cet anticorps anti-CD11b Polyclonal Lapin (ABIN3022180) détecte spécifiquement CD11b dans IHC, WB et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD11b anticorps (AA 145-340) (ABIN3022180)

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD11b est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-CD11b anticorps

Épitope: AA 145-340

Séquence: PQEDSDIAFL IDGSGSIIPH DFRRMKEFVS TVMEQLKKSK TLFSLMQYSE EFRIHFTFKE FQNNPNPRSL VKPITQLLGR THTATGIRKV VRELFNITNG ARKNAFKILV VITDGEKFGD PLGYEDVIPE ADREGVIRYV IGVGDAFRSE KSRQELNTIA SKPPRDHVFQ VNNFEALKTI QNQLREKIFA IEGTQT

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 145-340 of CD11b/ITGAM (NP_000623.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-CD11b (ABIN3022180)

Wang, Zheng, Gu, Cai, Wang, Zhang, Chen, Situ, Lin, Wang: "Network-pharmacology-based validation of TAMS/CXCL-1 as key mediator of XIAOPI formula preventing breast cancer development and metastasis." dans: Scientific reports, Vol. 7, Issue 1, pp. 14513, (2017) (PubMed).

Détails sur CD11b

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Autre désignation: ITGAM

Sujet: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.,CD11B,CR3A,MAC-1,MAC1A,MO1A,SLEB6,ITGAM,CD11b/ITAM,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Neuroscience,Cell Type Marker,Stem Cells,Hematopoietic Progenitors,Mesenchymal Stem Cells,Microglia marker,ITGAM

Poids moléculaire: 127 kDa

ID gène: 3684

UniProt: P11215

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation