CDC25C anticorps (AA 174-473)
Aperçu rapide pour CDC25C anticorps (AA 174-473) (ABIN3022370)
Antigène
Voir toutes CDC25C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 174-473
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Séquence
- PKLDKNPNLG EDQAEEISDE LMEFSLKDQE AKVSRSGLYR SPSMPENLNR PRLKQVEKFK DNTIPDKVKK KYFSGQGKLR KGLCLKKTVS LCDITITQML EEDSNQGHLI GDFSKVCALP TVSGKHQDLK YVNPETVAAL LSGKFQGLIE KFYVIDCRYP YEYLGGHIQG ALNLYSQEEL FNFFLKKPIV PLDTQKRIII VFHCEFSSER GPRMCRCLRE EDRSLNQYPA LYYPELYILK GGYRDFFPEY MELCEPQSYC PMHHQDHKTE LLRCRSQSKV QEGERQLREQ IALLVKDMSP
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 174-473 of human CDC25C (NP_001781.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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: "1,2:5,6-dianhydrogalactitol inhibits human glioma cell growth in vivo and in vitro by arresting the cell cycle at G2/M phase." dans: Acta pharmacologica Sinica, Vol. 38, Issue 4, pp. 561-570, (2017) (PubMed).
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- CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
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Autre désignation
- CDC25C
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Sujet
- This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described.,CDC25C,CDC25,PPP1R60,Epigenetics & Nuclear Signaling,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,CDC25C
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Poids moléculaire
- 45 kDa/48 kDa/50 kDa/53 kDa
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ID gène
- 995
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UniProt
- P30307
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Pathways
- Cycle Cellulaire, M Phase
Antigène
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