CDC25C anticorps

N° du produit ABIN1724739

Cité dans 2 publications. Cet anticorps anti-CDC25C Monoclonal Souris (Clone 1F12) (ABIN1724739) détecte spécifiquement CDC25C dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CDC25C anticorps (ABIN1724739)

Antigène: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDC25C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 1F12

Détail du produit anti-CDC25C anticorps

Fonction: CDC25C Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CDC25C expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CDC25C (ABIN1724739)

Zheng, Kosti, Loffredo, Bowman, Mechanic, Perlmutter, Jones, Shields, Harris: "Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study." dans: International journal of cancer. Journal international du cancer, Vol. 126, Issue 9, pp. 2199-210, (2010) (PubMed).

Busch, Barton, Morgenstern, Götz, Günther, Noll, Montenarh: "The G2/M checkpoint phosphatase cdc25C is located within centrosomes." dans: The international journal of biochemistry & cell biology, Vol. 39, Issue 9, pp. 1707-13, (2007) (PubMed).

Détails sur CDC25C

Antigène: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Autre désignation: CDC25C

Sujet: Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Poids moléculaire: 58 kDa

ID gène: 995

UniProt: P30307

Pathways: Cycle Cellulaire, M Phase